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Appetite 150 , 104575 (2020)

Beginning at 2.5 mg may reduce side effects such as nausea or stomach discomfort before increasing the dose

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There are a few key underlying principles

It helps keep blood sugar in a healthy range through several coordinated actions: it stimulates the pancreas to release insulin in a glucose-dependent way, it suppresses glucagon (the hormone that raises blood sugar), it slows how quickly the stomach empties, and it signals the brain to reduce appetite

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